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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
1.82
Human Site:
S498
Identified Species:
3.64
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S498
T
S
S
I
L
R
N
S
K
T
I
K
F
H
G
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
W360
V
R
N
A
T
F
T
W
A
R
S
D
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
L460
L
T
A
I
A
V
F
L
S
L
L
P
L
N
F
Dog
Lupus familis
XP_547113
1504
165780
M498
T
S
C
I
I
R
N
M
K
M
V
K
S
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
S501
R
T
V
R
T
I
K
S
H
G
W
E
H
A
F
Rat
Rattus norvegicus
O88269
1502
164977
S501
R
T
V
R
T
I
K
S
H
G
W
E
C
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
I524
M
H
E
I
L
N
G
I
K
V
L
K
L
Y
A
Chicken
Gallus gallus
Q5F364
1525
170953
I511
M
N
E
I
L
N
G
I
K
V
L
K
L
Y
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
I511
M
N
E
V
L
N
G
I
K
V
L
K
L
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
P403
D
T
V
P
G
N
P
P
S
N
N
N
E
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
M511
T
N
E
M
L
N
Y
M
R
V
I
K
F
Q
A
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
I494
I
S
E
I
L
N
N
I
K
S
L
K
L
Y
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
60
N.A.
6.6
6.6
N.A.
26.6
26.6
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
33.3
73.3
N.A.
20
20
N.A.
40
46.6
N.A.
46.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
0
9
0
0
0
0
25
42
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% D
% Glu:
0
0
42
0
0
0
0
0
0
0
0
17
9
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
17
0
25
% F
% Gly:
0
0
0
0
9
0
25
0
0
17
0
0
0
0
17
% G
% His:
0
9
0
0
0
0
0
0
17
0
0
0
9
17
0
% H
% Ile:
9
0
0
50
9
17
0
34
0
0
17
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
50
0
0
59
0
0
0
% K
% Leu:
9
0
0
0
50
0
0
9
0
9
42
0
42
0
0
% L
% Met:
25
0
0
9
0
0
0
17
0
9
0
0
0
0
0
% M
% Asn:
0
25
9
0
0
50
25
0
0
9
9
9
0
9
0
% N
% Pro:
0
0
0
9
0
0
9
9
0
0
0
9
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
17
9
0
17
0
17
0
0
9
9
0
0
0
0
0
% R
% Ser:
0
25
9
0
0
0
0
25
17
9
9
0
9
0
0
% S
% Thr:
25
34
0
0
25
0
9
0
0
9
0
0
0
0
9
% T
% Val:
9
0
25
9
0
9
0
0
0
34
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _